Enrollment open: 1,500 original practice questions built on NABP’s official MPJE Competency Statements. Enroll today and start with the free sample exam.
The Massachusetts MPJE — the Multistate Pharmacy Jurisprudence Examination as administered for Massachusetts licensure — tests federal pharmacy law and Massachusetts pharmacy law in a single sitting, with no distinction between them: where the Massachusetts rule and the federal rule differ, the Massachusetts rule is the one the question is answered under. PassProfessor’s Massachusetts MPJE program prepares you with 1,500 original practice questions built exactly that way — an 800-question federal core intermixed with 700 Massachusetts-specific questions grounded in the General Laws chapters 112 and 94C, the Board of Registration in Pharmacy regulations at 247 CMR, the Department of Public Health’s controlled-substance rules, and the Commonwealth’s mandatory-interchange law — weighted to NABP’s current Competency Statements.
What the program covers
Every competency area on NABP’s current MPJE Competency Statements is covered at its published weight. The bank’s question count in each area, and what a full practice exam draws from each:
- Licensure and Personnel — 333 practice questions; 22 per full practice exam
- Pharmacist Practice — 498 practice questions; 33 per full practice exam
- Dispensing Requirements — 358 practice questions; 24 per full practice exam
- Pharmacy Operations — 311 practice questions; 21 per full practice exam
A full practice exam draws 100 scored questions — the scored length of the real exam — across all four competency areas at their published weights, inside a 150-minute limit that mirrors the real 2.5-hour clock. The real exam administers 120 questions: the same 100 scored questions plus 20 unscored pretest questions mixed in; this program’s draws are scored questions only. Results on the real exam are reported pass/fail against the passing standard Massachusetts publishes: a score of at least 75 under 247 CMR 3.01 — a scaled examination score, not a percentage of questions answered correctly. Practice exams here are scored against a 70% practice benchmark: treat the benchmark as a practice target, not the examination standard.
How the program works
Enroll once and the full course opens: full-length practice exams, a free 12-question sample to start with, and per-topic drills for focused work on the competency areas you want to strengthen. Every practice exam draws a fresh set of questions, so repeat attempts keep testing rather than repeating. Every question in the program includes an explanation of why the keyed answer is right.
Massachusetts MPJE at a glance
- Questions on the real exam: 120 administered (100 scored + 20 unscored pretest)
- Time limit: 2.5 hours
- Format: computer-based at Pearson VUE; federal and Massachusetts questions intermixed, with no distinction between them
- Passing standard: a score of at least 75, set by Massachusetts regulation (247 CMR 3.01)
- Attempts: up to 5 per jurisdiction
- Fees: about $270 per attempt in NABP fees
- Eligibility: confirmed by the Massachusetts Board of Registration in Pharmacy
- Score transfer: Massachusetts regulation has no score-transfer provision — a Massachusetts pass applies to Massachusetts licensure
The Massachusetts law behind the exam
Half of what makes the Massachusetts MPJE hard is that it is two bodies of law at once. The Massachusetts half of this program is built on:
- The Massachusetts questions in this bank are grounded in primary Massachusetts sources read first-hand: the pharmacy practice statutes (Massachusetts General Laws chapter 112, sections 24 through 42D), the Controlled Substances Act (chapter 94C), the Board of Registration in Pharmacy regulations (247 CMR), the Department of Public Health controlled-substance regulations (105 CMR 700.000), the codified fee schedule (801 CMR 4.02), and the 2024 through 2026 session laws. The rulebook has moved recently: chapters 3, 6, 8 and 10 of 247 CMR were amended in 2025, the Shield Law 2.0 changes took effect in November 2025 and January 2026, and the pharmacist prescribing statute was rewritten in 2025. This bank keys on current law throughout, including those changes.
- Massachusetts’s prescription monitoring program rewards careful reading, because the familiar name trap fires here in reverse. The statute — chapter 94C, section 24A — enacts no proper name for the program at all; the operating name, MassPAT, the Massachusetts Prescription Awareness Tool, appears only in the Department of Public Health’s regulations. The Department of Public Health administers the program, not the Board of Registration in Pharmacy. Each pharmacy that delivers a Schedule II, III, IV or V controlled substance — or a designated additional drug — to the ultimate user reports at least once every 24 hours. The look-up duty sits on the prescriber, who must use the program each time a Schedule II or III narcotic or a benzodiazepine is issued; pharmacists carry a program training requirement and must register with MassPAT and maintain a login, but no rule requires a pharmacist to check the program before dispensing. Gabapentin is reported to the program as an additional drug even though it is not a scheduled controlled substance in Massachusetts, and since November 2025 medications for reproductive and gender-affirming health care are excluded from the program unless the Department determines reporting is necessary to protect the public health. Program data are confidential, and law enforcement reaches them only with a probable-cause warrant.
- Massachusetts controlled-substance practice runs on its own numbers. The schedules are established by the Commissioner of Public Health by regulation, and Schedule VI holds every prescription drug outside Schedules I through V. Registration splits by registrant: practitioners register with the Commissioner, while pharmacies and wholesale druggists register with the Board. Electronic prescribing is the baseline for controlled substances, with a closed list of exceptions. A Schedule II prescription becomes invalid thirty days after it is issued; a single filling may run to a ninety-day supply for substance-use-disorder treatment, non-opioid Schedule II and III drugs, and implantable infusion pumps, and to thirty days for everything else in Schedules II and III. The statute sets no expiration ceiling for Schedules III and IV — the six-month, five-refill ceiling exists only for Schedule V, and only as a Board regulation. An adult’s first outpatient opiate prescription, and any opiate prescription for a minor, is capped at a seven-day supply, and Massachusetts sets no morphine-milligram-equivalent threshold anywhere in its codified law. Patients may ask for a partial fill of any Schedule II prescription, with the remainder fillable only by the same pharmacy. And when a Schedule VI prescription has expired or run out of refills and the prescriber cannot be reached, the pharmacist may dispense no more than a fourteen-day supply or the smallest available unit-of-use package — the seventy-two-hour figure sometimes quoted is a MassHealth payment rule, not dispensing authority.
- Substitution in Massachusetts is mandatory, not permissive: unless the practitioner indicates ‘no substitution,’ the pharmacist shall dispense an interchangeable product — an abuse-deterrent product if one exists, otherwise the less expensive reasonably available interchangeable — and the label reads ‘Interchange,’ followed by the name of the product actually dispensed. Interchangeable products come from the Massachusetts List of Interchangeable Drugs: Orange Book A-rated products, plus the Commonwealth’s own Additional List and Exception List. Biological products run the other way — substitution is permitted rather than required, a written patient-specific instruction is what bars it, and the prescriber must be notified within a reasonable time; Massachusetts fixes no day count, and the five-day rule found in other states’ materials is not Massachusetts law. Pharmacy benefit managers are licensed by the Division of Insurance under chapter 176Y, enacted in 2024 — a different subject from the same-day market-review act. Pharmacist scope has widened on verified lines: pharmacists prescribe and dispense hormonal contraceptives and, under the 2025 amendment to section 19F of chapter 94C, medications for HIV and STI treatment and prevention; and qualified pharmacy personnel vaccinate patients age five and older under Department of Public Health policy, though technician trainees may never vaccinate.
- The people rules run on split calendars. The Board of Registration in Pharmacy has thirteen members serving three-year terms, no more than two consecutive. Pharmacists in training complete at least 1,500 internship hours — at least 1,000 of them in a pharmacy setting and at least 500 in clinical-type settings; the older ‘no more than 500’ phrasing in some materials states the opposite of current law. Licensure takes a score of at least 75 on both the NAPLEX and the MPJE, and the two examinations are paired: fail either one and reapplication must come within a year of the original sitting, or both must be retaken. Pharmacy technicians are licensed in Massachusetts, not registered, in three tiers — trainee, technician, and certified pharmacy technician — and one pharmacist may supervise four support staff only on the regulation’s conditions, otherwise three. A manager of record may manage only one pharmacy at a time and must average at least thirty hours a week there. Personal pharmacist licenses expire December 31 of even-numbered years, while pharmacy permits expire December 31 of odd-numbered years. Continuing education is twenty hours every calendar year — at least two in pharmacy law, no more than fifteen by home study, and no carrying hours from one year into the next — and a pharmacist whose license has lapsed by more than two years must pass the MPJE again to restore it. The regulations contain no score-transfer provision: pharmacists licensed elsewhere enter by reciprocity, pass the Massachusetts MPJE, and are not required to retake the NAPLEX.
What changes on March 1, 2027
- From March 1, 2027, NABP replaces the MPJE Competency Statements with a new Content Outline — Pharmacy and Pharmacist Practice 30%, Medication Use Process 30%, Regulatory Authority and Legal Obligations 20%, Pharmacy Operations 20%.
- Every question in this bank is dual-tagged to both blueprints, so this program’s practice exams re-weight to the new outline when the change takes effect — the questions you are practicing now stay the right questions.
Three things worth knowing
- One scoring point to be clear about: the 70% figure used inside this program is a practice benchmark only. Massachusetts publishes its passing score — at least 75 under 247 CMR 3.01 — and that 75 is a scaled examination score, not a percentage of questions to answer correctly; no percentage, ours or anyone else’s, is the passing standard.
- One portability point: MPJE scores are not transferable, and Massachusetts regulation contains no score-transfer provision at all. (Score transfer belongs to the separate uniform UMPJE, used in 13 other jurisdictions.) This program prepares you for the Massachusetts MPJE specifically.
- One scope point: the 800-question federal core is the same law every MPJE state tests, but the 700 Massachusetts questions key on Massachusetts law. If you later seek licensure in another MPJE state, you will need that state’s law exam preparation, not Massachusetts’s.
For the detailed walk-through of the exam’s format, scoring and rules, read the Massachusetts MPJE Exam Guide.